The nursery rhyme, "Itsy Bitsy Spider", was adapted into an ongoing animated series in 1994 by Paramount, Hyperion, & USA Network, airing on Friday evenings & Sunday mornings, as memory serves.
Itsy Bitsy Spider revolves around the titular arachnid (Frank Welker) and his human friend, who tries to protect Itsy from the Exterminator (Matt Frewer, ex-Max Headroom), and a snooty governess (Charlotte Rae, ex-The Facts of Life).
Unfortunately, no episodes are available on YouTube. All we have is the intro.
USA got 2 seasons of 13 episodes each, but after it was cancelled in 1996, Itsy Bitsy Spider has been left to languish in Paramount's vaults. There was a feature film by the same name, but with no connection to the show.