Cartoon Network's European division co-produced the series, which aired first on Fox before moving to CN here in the US. The series launched in the spring of 2002 as a mid-season replacement series, and lasted 4 seasons before being yanked. However, 4Kids, which began programming Fox's Saturday lineup in the fall of '02, brought the show back in 2006 to finish the run.
Aside from the odd pigmentation on Wayne (the blue skinned one), he & Lucien behave the same way most brothers do. They argue, they fight, they prank each other. Typical stuff.
Dailymotion offers a sample episode.
Cramp Twins has the distinction of being Sunbow Entertainment's last series. What a way to go, eh wot?